Pan-Cancer & Cancer type-specific
Driver Missense Mutation Prediction Platform

MutDrive is a comprehensive analysis platform integrating protein language model and sequence-structure multimodal fusion technology, designed to assist bioinformatics researchers and clinical investigators in efficiently identifying Driver Mutations and Passenger Mutations.

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Core Capabilities

Integrating the latest deep learning technologies with bioinformatics knowledge to provide comprehensive mutation analysis solutions

Pan-Cancer Prediction

Fine-tuning the Lucaone protein language model with LORA to achieve high generalization performance in identifying pan-cancer driver mutations

Cancer type-specific prediction

Using sequence-structure multimodal information to achieve cancer type-specific driver mutation prediction

Clinical-Grade Fast Inference

High-performance GPU cluster deployed in backend, supporting single mutation second-level response and large-scale CSV file batch upload analysis

Authoritative Dataset Validation

Validated by authoritative independent test sets such as dbMCS, achieving AUROC of 0.82, significantly outperforming traditional algorithms

Prediction Models

Choose the most suitable model for your use case, from clinical diagnosis to large-scale screening

Pan-Cancer Prediction Model

Universal prediction model applicable to multiple cancer types, supporting single sequence and batch CSV file prediction

  • Multi-cancer coverage
  • High generalizability
  • Batch processing
  • CSV file upload

Cancer type-specific Prediction Model

Professional model optimized for specific cancer types, providing more accurate cancer-specific predictions

  • Gastroesophageal Cancer
  • Leukemia
  • Lung Cancer
  • Cancer-specific optimization

Prediction Results Description

Driver Mutation

Driver mutations are mutations that promote tumor development and progression, typically with high clinical significance.

Passenger Mutation

Passenger mutations are neutral mutations that have no significant role in promoting tumor development.

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Upload your mutation data and get professional pathogenicity prediction reports instantly

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